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CYB5R1 Protein (His tag)

CYB5R1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 97 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7317282
  • Target Alle CYB5R1 Proteine anzeigen
    CYB5R1 (Cytochrome B5 Reductase 1 (CYB5R1))
    Protein-Typ
    Recombinant
    Spezies
    • 5
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 2
    • 2
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses CYB5R1 Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human CYB5R1 Protein (His Tag)
    Sequenz
    Leu 29-Tyr 305
    Produktmerkmale
    A DNA sequence encoding the human CYB5R1 (Q9UHQ9) (Leu 29-Tyr 305) was expressed, with a polyhistidine tag at the N-terminus.
    Reinheit
    > 97 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product CYB5R1 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CYB5R1 (Cytochrome B5 Reductase 1 (CYB5R1))
    Andere Bezeichnung
    CYB5R1 (CYB5R1 Produkte)
    Synonyme
    B5R.1 Protein, B5R1 Protein, B5R2 Protein, NQO3A2 Protein, humb5R2 Protein, 1500005G05Rik Protein, C80155 Protein, Nqo3a2 Protein, NAD(P)H:quinone oxidoreductase type 3, polypeptide A2 Protein, cytochrome b5 reductase 1 Protein, CYB5R1 Protein, Cyb5r1 Protein
    Hintergrund

    Background: Tyrosinase-related protein 1, also known as TYRP1 or TRP1, is a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Mutations in this enzyme are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III. TYRP1 / TRP1 is involved in the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. This enzyme may regulate or influence the type of melanin synthesized. The expression of Tyrosinase-related protein 1 (TYRP1) is regulated by the microphthalmia-associated transcription factor (MITF). There is mounting evidence demonstrating that in addition to its role in eumelanin synthesis, TYRP1 is involved in maintaining stability of tyrosinase proliferation and melanocyte cell death.

    Synonym: B5R.1,B5R1,B5R2,humb5R2,NQO3A2,PRO9865,UNQ3049

    Molekulargewicht
    33.5 kDa
    UniProt
    Q9UHQ9
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