CYB5R1 Protein (His tag)
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- Target Alle CYB5R1 Proteine anzeigen
- CYB5R1 (Cytochrome B5 Reductase 1 (CYB5R1))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses CYB5R1 Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Human CYB5R1 Protein (His Tag)
- Sequenz
- Leu 29-Tyr 305
- Produktmerkmale
- A DNA sequence encoding the human CYB5R1 (Q9UHQ9) (Leu 29-Tyr 305) was expressed, with a polyhistidine tag at the N-terminus.
- Reinheit
- > 97 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product CYB5R1 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- CYB5R1 (Cytochrome B5 Reductase 1 (CYB5R1))
- Andere Bezeichnung
- CYB5R1 (CYB5R1 Produkte)
- Synonyme
- B5R.1 Protein, B5R1 Protein, B5R2 Protein, NQO3A2 Protein, humb5R2 Protein, 1500005G05Rik Protein, C80155 Protein, Nqo3a2 Protein, NAD(P)H:quinone oxidoreductase type 3, polypeptide A2 Protein, cytochrome b5 reductase 1 Protein, CYB5R1 Protein, Cyb5r1 Protein
- Hintergrund
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Background: Tyrosinase-related protein 1, also known as TYRP1 or TRP1, is a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Mutations in this enzyme are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III. TYRP1 / TRP1 is involved in the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. This enzyme may regulate or influence the type of melanin synthesized. The expression of Tyrosinase-related protein 1 (TYRP1) is regulated by the microphthalmia-associated transcription factor (MITF). There is mounting evidence demonstrating that in addition to its role in eumelanin synthesis, TYRP1 is involved in maintaining stability of tyrosinase proliferation and melanocyte cell death.
Synonym: B5R.1,B5R1,B5R2,humb5R2,NQO3A2,PRO9865,UNQ3049
- Molekulargewicht
- 33.5 kDa
- UniProt
- Q9UHQ9
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