Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1) protein (His tag)

Produktnummer ABIN7195354

Produktdetails

Target: Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)

Protein-Typ: Recombinant

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Aufreinigungstag / Konjugat: His tag

Verwendungszweck: Recombinant Human CMPK1 Protein (His Tag)

Sequenz: Met 1-Gly 196

Produktmerkmale: A DNA sequence encoding the human CMPK1 (P30085) (Met1-Gly196) was fused with a polyhistide tag at the N-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen, Liquid

Buffer: Supplied as sterile 20 mM Tris, 500 mM Nacl, pH 7.4, 10 % glycerol

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Antigendetails

Target: Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)

Andere Bezeichnung: CMPK1 (CMPK1 Produkte)

Synonyme: CK Protein, CMK Protein, CMPK Protein, UMK Protein, UMP-CMPK Protein, UMPK Protein, UMP/CMPK Protein, PSPTO1749 Protein, cmpk1 Protein, fb52d08 Protein, fk47a07 Protein, ump Protein, wu:fb52d08 Protein, wu:fk47a07 Protein, zgc:56452 Protein, Cmpk Protein, RGD1310116 Protein, cmpk Protein, 0610011D08Rik Protein, UMP-CMPk Protein, UCK Protein, cytidine/uridine monophosphate kinase 1 Protein, cytidylate kinase Protein, cytidine monophosphate (UMP-CMP) kinase 1, cytosolic Protein, cytidine monophosphate (UMP-CMP) kinase 1, cytosolic S homeolog Protein, cytidylate kinase Cmk Protein, cytidine monophosphate (UMP-CMP) kinase 1 Protein, CMPK1 Protein, cmk Protein, cmpk1 Protein, cmpk Protein, Cmpk1 Protein, cmpk1.S Protein, Mrub_0478 Protein, MMAH_RS06670 Protein, TAGG_RS04320 Protein, Trad_0784 Protein, Deba_2713 Protein, Toce_1154 Protein, VDIS_RS03585 Protein, Fbal_1939 Protein, Ilyop_1379 Protein, Lbys_3481 Protein, Calni_0093 Protein, Ftrac_1556 Protein, Ocepr_1777 Protein

Hintergrund:

Background: CMPK1 plays a key role in the maintenance of pyrimidine nucleotide pool profile and for the metabolism of pyrimidine analogs in cells. It catalyzes the phosphoryl transfer from ATP to UMP, CMP, and deoxy-CMP (dCMP), resulting in the formation of ADP and the corresponding nucleoside diphosphate. CMPK1 also has a significant role in the activation of pyrimidine analogs, which are clinically useful anti-cancer and anti-viral drugs. In the meanwhile, CMPK1 functions in cellular nucleic acid biosynthesis.

Synonym: CK,CMK,CMPK,UMK,UMP-CMPK,UMPK

Molekulargewicht: 24.5 kDa

UniProt: P30085

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process