DMP1 Protein (His tag)

Produktnummer ABIN7318398

Produktdetails

Target: DMP1 (DMTF1) (Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses DMP1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human DMP1 Protein (His Tag)

Sequenz: Lys17-Tyr513

Produktmerkmale: Recombinant Human Dentin matrix protein 1 is produced by our Mammalian expression system and the target gene encoding Lys17-Tyr513 is expressed with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: DMP1 (DMTF1) (Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1))

Andere Bezeichnung: DMP1 (DMTF1 Produkte)

Synonyme: DMP1 Protein, DMTF Protein, hDMP1 Protein, Dimp Protein, Dmp1 Protein, DMTF1 Protein, zgc:92448 Protein, cyclin D binding myb like transcription factor 1 Protein, cyclin D binding myb-like transcription factor 1 Protein, DMTF1 Protein, Dmtf1 Protein, dmtf1 Protein

Hintergrund:

Background: Dentin Matrix Acidic Phosphoprotein 1 (DMP-1) is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. DMP-1 is expressed in teeth particularly in odontoblast, ameloblast, and cementoblast. DMP-1 is critical for proper mineralization of bone and dentin. DMP-1 may have a dual function during osteoblast differentiation. In the nucleus of undifferentiated osteoblasts, the unphosphorylated form of DMP-1 acts as a transcriptional component for activation of osteoblast-specific genes like osteocalcin. During the osteoblast to osteocyte transition phase, DMP-1 is phosphorylated and exported into the extracellular matrix, where it regulates nucleation of hydroxyapatite. DMP-1 mutations have also been shown to cause rickets hypophosphatemic autosomal recessive type 1 (ARHR1).

Synonym: Dentin Matrix Acidic Phosphoprotein 1, DMP-1, Dentin Matrix Protein 1, DMP1,ARHP,ARHR

Molekulargewicht: 55.0 kDa

UniProt: Q13316