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CFHR5 Protein (His tag)

CFHR5 Spezies: Human Wirt: Human Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7318330
  • Target Alle CFHR5 Proteine anzeigen
    CFHR5 (Complement Factor H-Related 5 (CFHR5))
    Protein-Typ
    Recombinant
    Spezies
    Human
    Quelle
    • 1
    • 1
    • 1
    • 1
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses CFHR5 Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human CFHR5 Protein (His Tag)
    Sequenz
    Glu19-Glu569
    Produktmerkmale
    Recombinant Human Complement Factor H-Related 5 is produced by our Mammalian expression system and the target gene encoding Glu19-Glu569 is expressed with a 6His tag at the C-terminus.
    Reinheit
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CFHR5 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CFHR5 (Complement Factor H-Related 5 (CFHR5))
    Andere Bezeichnung
    CFHR5 (CFHR5 Produkte)
    Synonyme
    CFHL5 Protein, CFHR5D Protein, FHR-5 Protein, FHR5 Protein, complement factor H related 5 Protein, CFHR5 Protein
    Hintergrund

    Background: Complement factor H-related protein 5(FHR-5 for short), is a secreted protein which contains 9 Sushi (CCP/SCR) domains. It is expressed by the liver and secreted in plasma. The pattern of the deposits is similar to other complement components, suggesting that FHR-5 may play a role in complement activation and regulation. Defects in CFHR5 have been found in patients with atypical hemolytic uremic syndrome and may contribute to the disease. In contrast to typical hemolytic uremic syndrome, atypical forms have a poorer prognosis, with higher death rates and frequent progression to end-stage renal disease.

    Synonym: Complement factor H-related protein 5,CFHR5,CFHL5,FHR5

    Molekulargewicht
    63.5 kDa
    UniProt
    Q9BXR6
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