Chromogranin A Protein (CHGA) (His tag)
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- Target Alle Chromogranin A (CHGA) Proteine anzeigen
- Chromogranin A (CHGA)
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
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Spezies
- Maus
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses Chromogranin A Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Mouse Chromogranin-A/Chga protein (His Tag)
- Sequenz
- 457Ile-717Leu
- Produktmerkmale
- A DNA sequence encoding theMouse Chromogranin-A/Chga(P26339) (457Ile-717Leu) was expressed with a polyhistidine tag at the N-terminus.
- Reinheit
- >90 % as determined by reducing SDS-PAGE.
- Biological Activity Comment
- Immunogen(E-AB-40339)
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- Chromogranin A (CHGA)
- Andere Bezeichnung
- Chromogranin-A/Chga (CHGA Produkte)
- Synonyme
- CGA Protein, CG-ALPHA Protein, FSHA Protein, GPHA1 Protein, GPHa Protein, HCG Protein, LHA Protein, TSHA Protein, ChrA Protein, fj05f09 Protein, si:dkey-177p2.2 Protein, wu:fj05f09 Protein, zgc:101749 Protein, zgc:56075 Protein, CHGA Protein, cgA Protein, chga Protein, chromogranin A Protein, glycoprotein hormones, alpha polypeptide Protein, uncharacterized CHGA Protein, chromogranin A S homeolog Protein, CHGA Protein, CGA Protein, Chga Protein, chga Protein, chga.S Protein
- Hintergrund
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Background: Pancreastatin: Strongly inhibits glucose induced insulin release from the pancreas.Catestatin: Inhibits catecholamine release from chromaffin cells and noradrenergic neurons by acting as a non-competitive nicotinic cholinergic antagonist. Can induce mast cell migration, degranulation and production of cytokines and chemokines.Serpinin: Regulates granule biogenesis in endocrine cells by up-regulating the transcription of protease nexin 1 (SERPINE2) via a cAMP-PKA-SP1 pathway. This leads to inhibition of granule protein degradation in the Golgi complex which in turn promotes granule formation . Pyroglutaminated (pGlu)-serpinin exerts an antiapoptotic effect on cells exposed to oxidative stress .
Synonym: beta Granin,betagranin (N-terminal fragment of chromogranin A),catestatin,CgA,CHG A,Chga,chromofungin,Chromogranin A,Chromogranin A parathyroid secretory protein 1,Chromogranin A precursor,ChromograninA,CMGA,ER-37,Pancreastatin,Parastatin,Parathyroid secretory protein 1,Pituitary secretory protein I,Secretory protein I,SP I,SP-I,SP1,SPI,Vasostatin,Vasostatin I,Vasostatin II
- Molekulargewicht
- 31kDa
- UniProt
- P26339
- Pathways
- Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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