CHRNB3 Protein (His tag)

Produktnummer ABIN7318819

Produktdetails

Target: CHRNB3 (Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses CHRNB3 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human CHRNB3 Protein (His Tag)

Sequenz: Ile25-Leu232

Produktmerkmale: Recombinant Human Neuronal acetylcholine receptor subunit beta-3 is produced by our Mammalian expression system and the target gene encoding Ile25-Leu232 is expressed with a 6His tag at the C-terminus.

Reinheit: > 90 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: CHRNB3 (Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3))

Andere Bezeichnung: CHRNB3 (CHRNB3 Produkte)

Synonyme: 5730417K16Rik Protein, Acrb3 Protein, NACHR Protein, CHRNB3 Protein, chrnb3 Protein, cholinergic receptor nicotinic beta 3 subunit Protein, neuronal acetylcholine receptor subunit beta-3 Protein, cholinergic receptor, nicotinic, beta polypeptide 3 Protein, cholinergic receptor, nicotinic beta 3 L homeolog Protein, cholinergic receptor, nicotinic beta 3 Protein, cholinergic receptor, nicotinic, beta 3b (neuronal) Protein, cholinergic receptor, nicotinic, beta polypeptide 3a Protein, CHRNB3 Protein, CpipJ_CPIJ012638 Protein, Chrnb3 Protein, chrnb3.L Protein, chrnb3 Protein, chrnb3b Protein, chrnb3a Protein

Hintergrund:

Background: Neuronal acetylcholine receptor subunit beta-3(CHRNB3) is a cell membrane protein and belongs to the ligand-gated ion channel (TC 1.A.9) family. CHRNB3 seems to be composed of two different type of subunits: alpha and beta. The CHRNB3 are (hetero) pentamers composed of homologous subunits. The subunits that make up the muscle and neuronal forms of CHRNB3 are encoded by separate genes and have different primary structure. There are several subtypes of neuronal CHRNB3 that vary based on which homologous subunits are arranged around the central channel. They are classified as alpha-subunits if like muscle alpha-1, they have a pair of adjacent cysteines as part of the presumed acetylcholine binding site. Subunits lacking these cysteine residues are classified as beta-subunits.

Synonym: Neuronal acetylcholine receptor subunit beta-3

Molekulargewicht: 25.3 kDa

UniProt: Q05901