CXCL6 Protein (His tag)

Produktnummer ABIN7319813

Produktdetails

Target: CXCL6 (Chemokine (C-X-C Motif) Ligand 6 (CXCL6))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses CXCL6 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human C-X-C Motif Chemokine 6/CXCL6 (C-6His)

Sequenz: Gly38-Asn114

Produktmerkmale: Recombinant Human C-X-C Motif Chemokine 6 is produced by our Mammalian expression system and the target gene encoding Gly38-Asn114 is expressed with a 6His tag at the C-terminus.

Reinheit: >95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 5 % Trehalose, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: CXCL6 (Chemokine (C-X-C Motif) Ligand 6 (CXCL6))

Andere Bezeichnung: C-X-C Motif Chemokine 6/CXCL6 (CXCL6 Produkte)

Synonyme: CKA-3 Protein, GCP-2 Protein, GCP2 Protein, SCYB6 Protein, Cxcl6 Protein, CXCL5 Protein, C-X-C motif chemokine ligand 6 Protein, chemokine (C-X-C motif) ligand 5 Protein, CXCL6 Protein, Cxcl6 Protein, CXCL5 Protein

Hintergrund:

Background: Chemokine (C-X-C-Motif) Ligand 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family. It is a potent neutrophil chemotactic and activating factor and it exhibits extensive similarity to other CXC chemokines such as IL-8 and ENA-78. CXCL6 can promote the release of MMP-9 from granulocytes indicating its potential role as an inflammatory mediator. It functionally uses both of the IL-8/CXCL8 receptors to chemoattract neutrophils but that is structurally most related to epithelial cell-derived neutrophil attractant-78 (ENA-78)/CXCL5. The human CXCL6 gene has been cloned and is physically mapped to the CXC chemokine locus on chromosome 4. Mature human CXCL6 is a 75 amino acid (aa) protein with a predicted molecular weight of approximately 8 kDa. Human CXCL6 shares 60 % and 67 % aa identity with mouse and bovine CXCL6, respectively.

Synonym: C-X-C Motif Chemokine 6, Chemokine Alpha 3, CKA-3, Granulocyte Chemotactic Protein 2, GCP-2, Small-Inducible Cytokine B6, CXCL6, GCP2, SCYB6

Molekulargewicht: 9.35 kDa

UniProt: P80162