CD207 Protein (His tag)
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- Target Alle CD207 Proteine anzeigen
- CD207 (CD207 Molecule, Langerin (CD207))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Human Cells
- Aufreinigungstag / Konjugat
- Dieses CD207 Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Human Langerin/CD207 Protein (His Tag)
- Sequenz
- Tyr64-Pro328(Val278Ala)
- Produktmerkmale
- Recombinant Human Langerin is produced by our Mammalian expression system and the target gene encoding Tyr64-Pro328(Val278Ala) is expressed with a 6His tag at the N-terminus.
- Reinheit
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CD207 Protein
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CD207 Molecule, Langerin (CD207) (AA 1-328) protein (GST tag)
CD207 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
CD207 Molecule, Langerin (CD207) (AA 63-331) protein (His tag)Crystallography grade CD207 Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
CD207 Molecule, Langerin (CD207) (AA 1-328) protein (Strep Tag)Crystallography grade CD207 Spezies: Human Wirt: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
CD207 Molecule, Langerin (CD207) (AA 1-331) protein (Strep Tag)Crystallography grade CD207 Spezies: Maus Wirt: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
CD207 Molecule, Langerin (CD207) (AA 65-328) protein (His tag)CD207 Spezies: Human Wirt: Baculovirus infected Insect Cells Recombinant > 90 % by SDS - PAGE SDS
CD207 Molecule, Langerin (CD207) protein (Myc-DYKDDDDK Tag)CD207 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- CD207 (CD207 Molecule, Langerin (CD207))
- Andere Bezeichnung
- Langerin/CD207 (CD207 Produkte)
- Synonyme
- CD207 Protein, CLEC4K Protein, RGD1565913 Protein, CD207 molecule Protein, CD207 antigen Protein, CD207 Protein, Cd207 Protein
- Hintergrund
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Background: Langerin (CD207) is a type II transmembrane glycoprotein which is member K of the C-type lectin domain family. Langerin is used as a marker for Langerhans cells (LCs) which represent the immature dendritic cells in the epidermis. Langerin is necessary and sufficient for Birbeck granule formation. Human langerin sequence contains a 43 aa cytoplasmic domain, a 21 aa transmembrane domain and a 264 aa extracellular domain (ECD) that contains a coiled-coil domain and a single C-type lectin domain. Human langerin shares 68 % , 62 %, 71 % aa identity with mouse, rat and bovine langerin ECD, respectively. Trimerization greatly increases the lectin binding affinity. Langerin internalizes endogenous proteins such as type I procollagen. Internalization by LC is thought to lead to suppression of self reactions. Langerin also mediates endocytosis of non-peptide antigens containing mannose, N-acetyl glucosamine and fucose that are expressed by mycobacteria and fungae.
Synonym: CD207 antigen, langerin, CD207, C-type lectin domain family 4 member K, C-type lectin domainfamily 4, member K
- Molekulargewicht
- 31.5 kDa
- UniProt
- Q9UJ71
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