CD200R4 Protein (His tag)

Produktnummer ABIN7320208

Produktdetails

Target: CD200R4 (CD200 Receptor 4 (CD200R4))

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CD200R4 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Mouse CD200R4/CD200RLa Protein (His Tag)

Sequenz: Met 1-Thr 241

Produktmerkmale: A DNA sequence encoding the extracellular domain of mouse CD200R4 (NP_997127.1) (Met 1-Thr 241) was expressed, fused with a polyhistidine tag at the C-terminus.

Reinheit: > 96 % as determined by SDS-PAGE

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: CD200R4 (CD200 Receptor 4 (CD200R4))

Andere Bezeichnung: CD200R4/CD200RLa (CD200R4 Produkte)

Synonyme: F630107N04Rik Protein, MCD200RLa Protein, CD200 receptor 4 Protein, Cd200r4 Protein

Hintergrund:

Background: Cell surface glycoprotein CD200 receptor 4, also known as Cell surface glycoprotein OX2 receptor 4, CD200 cell surface glycoprotein receptor-like 4, CD200RLa, and CD200R4, is a single-pass type I  membrane protein which belongs to the CD200R family. CD200 (OX2) is a cell surface glycoprotein that interacts with a structurally related receptor (CD200R) expressed mainly on myeloid cells and is involved in regulation of macrophage and mast cell function. In mouse there are up to five genes related to CD200R with conflicting data as to whether they bind CD200. CD200R4 contains one Ig-like C2-type (immunoglobulin-like) domain and one Ig-like V-type (immunoglobulin-like) domain. CD200R4 is highly expressed in monocytes, NK cells and a subset of NKT cells. It is weakly expressed in granulocytes and B cells (at protein level). CD200R4 is also expressed in brain, lung, testis, thymus, intestine and uterus. and in bone marrow derived-macrophage and dendritic cells and mast cells. CD200R4 is involved in the recruitment or surface expression of the TYROBP receptor.

Synonym: Cd200r4;F630107N04Rik;MCD200RLa;CD200 Receptor 4

Molekulargewicht: 25 kDa

NCBI Accession: NP_997127