Cathepsin H Protein (CTSH) (AA 22-333) (His tag)

Produktnummer ABIN7320712

Produktdetails

Target: Cathepsin H (CTSH)

Protein-Typ: Recombinant

Proteineigenschaft: AA 22-333

Spezies: Maus

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses Cathepsin H Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Mouse Cathepsin H/CTSH Protein (aa 22-333, His Tag)

Sequenz: Glu22-Val333

Produktmerkmale: Recombinant Mouse Cathepsin H is produced by our Mammalian expression system and the target gene encoding Glu22-Val333 is expressed with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by SDS-PAGE

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: Cathepsin H (CTSH)

Andere Bezeichnung: Cathepsin H/CTSH (CTSH Produkte)

Synonyme: fc44c02 Protein, zgc:85774 Protein, wu:fc44c02 Protein, CTSH Protein, ACC-4 Protein, ACC-5 Protein, CPSB Protein, minichain Protein, AL022844 Protein, cathepsin H Protein, cathepsin H L homeolog Protein, ctsh Protein, CTSH Protein, ctsh.L Protein, Ctsh Protein

Hintergrund:

Background: Cathepsin H (CTSH), which can act both as an aminopeptidase and as an endopeptidase, is a lysosomal cysteine protease of the papain family. CTSH is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. CTSH is associated with various pathological conditions like human fibrous meningioma, colorectal cancer, arthritis, human prostate tumor and lung cancer. CTSH is associated with cancer progression because of their ability to degrade extracellular matrices facilitating invasion, angiogenesis and metastasis as is evident from numerous clinical reports and experimental models. The expression of CTSH is significantly increased in disease states such as in prostate tumors, sera of asthmatic patients, and mucosa of colorectal cancer patients.

Synonym: Pro-cathepsin H, CTSH, ACC-4, ACC-5, aleurain, cathepsin B3, cathepsin BA, cathepsin H, CPSB, minichain, N-benzoylarginine-beta-naphthylamide hydrolase

Molekulargewicht: 36.1 kDa

Pathways: Positive Regulation of Endopeptidase Activity