CES2 Protein (His tag)
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- Target Alle CES2 Proteine anzeigen
- CES2 (Carboxylesterase 2 (CES2))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
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Spezies
- Maus
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses CES2 Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Mouse Carboxylesterase-2/CES2 Protein (His Tag)(Active)
- Sequenz
- Met 1-Lys 557
- Produktmerkmale
- A DNA sequence encoding the extracellular domain of mouse CES2 (NP_663578.1) (Met 1-Lys 557) was expressed, with a polyhistidine tag at the C-terminus.
- Reinheit
- > 85 % as determined by SDS-PAGE
- Endotoxin-Niveau
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Measured by its ability to hydrolyze pnitrophenylacetate. The specific activity is >90,000 pmoles/min/μg.
- Top Product
- Discover our top product CES2 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- CES2 (Carboxylesterase 2 (CES2))
- Andere Bezeichnung
- Carboxylesterase-2/CES2 (CES2 Produkte)
- Synonyme
- CE-2 Protein, CES2A1 Protein, PCE-2 Protein, iCE Protein, Ces2 Protein, im:6908784 Protein, si:dkey-38l12.2 Protein, zgc:153863 Protein, ce-2 Protein, ces2a1 Protein, pce-2 Protein, carboxylesterase 2 Protein, liver carboxylesterase 2 Protein, cocaine esterase Protein, carboxylesterase 2 (intestine, liver) Protein, CES2 Protein, Ces2 Protein, LOC100343300 Protein, LOC100734360 Protein, ces2 Protein
- Hintergrund
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Background: Carboxylesterase 2 (CES2) is a member of the carboxylesterase family and belongs to the multigene family. Carboxylesterase 2 is responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and beroin. It also serves to hydrolyze long-chain fatty acid esters and thioesters. It is speculated that carboxylesterases may play a role in lipid metabolism and the blood-brain barrier system and together with isform 1, are a serine esterase involved in both drug metabolism and activation. Human carboxylesterase 2 is commonly expressed in tumor tissues and irinotecan, a topoisomerase I inhibitor commonly used in the treatment of many solid tumors.
Synonym: ces2A3
- Molekulargewicht
- 60.4 kDa
- NCBI Accession
- NP_663578
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