CLEC4E Protein (His tag)

Produktnummer ABIN7318316

Produktdetails

Target: CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses CLEC4E Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human CLEC4E/Mincel Protein (His Tag)

Sequenz: Arg41-Leu219

Produktmerkmale: Recombinant Human C-Type Lectin Domain Family 4 Member E is produced by our Mammalian expression system and the target gene encoding Arg41-Leu219 is expressed with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))

Andere Bezeichnung: CLEC4E/Mincel (CLEC4E Produkte)

Synonyme: CLECSF9 Protein, MINCLE Protein, C86253 Protein, Clecsf9 Protein, Mincle Protein, CLEC4E Protein, C-type lectin domain family 4 member E Protein, C-type lectin domain family 4, member e Protein, C-type lectin domain family 4, member E Protein, CLEC4E Protein, Clec4e Protein, LOC611538 Protein

Hintergrund:

Background: C-Type Lectin Domain Family 4 Member E (CLEC4E) is a 219 amino acid single-pass type II membrane protein that contains one C-type Lectin domain. It is expressed in monocytes, CLEC4E functions as a downstream target of C/EBP β and is thought to play a role in the inflammatory response, possibly via transcriptional control of C/EBP β. CLEC4E may play a role in the response to inflammatory stimuli in peritoneal macrophages and may be involved in immune surveillance processes under transcriptional control of CEBPB. Human CLEC4E shares 67 % sequence identity with its mouse counterpart, suggesting a similar function between species. CLEC-4E exists as multiple alternatively spliced isoforms that are encoded by a gene which maps to a natural killer gene complex region on human chromosome 12.

Synonym: C-Type Lectin Domain Family 4 Member E, C-Type Lectin Superfamily Member 9, Macrophage-Inducible C-Type Lectin, CLEC4E, CLECSF9, MINCLE

Molekulargewicht: 21.7 kDa

UniProt: Q9ULY5