CLEC3B Protein (His tag)

Produktnummer ABIN7320183

Produktdetails

Target: CLEC3B (C-Type Lectin Domain Family 3, Member B (CLEC3B))

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CLEC3B Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Mouse CLEC3B/Tetranectin Protein (His Tag)

Sequenz: Met 1-Val 202

Produktmerkmale: A DNA sequence encoding the mouse CLEC3B (P43025) (Met 1-Val 202) was expressed, with a C-terminal polyhistidinetag.

Reinheit: > 95 % as determined by SDS-PAGE

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: CLEC3B (C-Type Lectin Domain Family 3, Member B (CLEC3B))

Andere Bezeichnung: CLEC3B/Tetranectin (CLEC3B Produkte)

Synonyme: Tna Protein, clec3b Protein, tetn Protein, TN Protein, TNA Protein, C-type lectin domain family 3, member B Protein, C-type lectin domain family 3 member B Protein, tetranectin Protein, C-type lectin domain family 3, member b Protein, Clec3b Protein, clec3b Protein, CLEC3B Protein, tetn Protein

Hintergrund:

Background: Tetranectin (TN), also known as C-type lectin domain family 3, member B (CLEC3B) is a member of the C-type lectin Family. It is plasminogen kringle 4 binding protein and regulates fibrinolysis and proteolytic processes via binding to plasminogen. Tetranectin has been suggested to play a role in tissue remodeling, due to its ability to stimulate plasminogen activation and its expression in developing tissues such as developing bone and muscle. Tetranectin enhances plasminogen activation by a tissue-type plasminogen activator so that it has been suggested to play a role in tissue remodeling. Tetranectin may play a role in the wound healing process. Tetranectin may play a role in neurological diseases and may serve as a diagnostic aid in multiple sclerosis (MS). Tetranectin was found significantly under-expressed in both serum and saliva of metastatic oral squamous cell carcinoma (OSCC) compared to primary OSCC. Tetranectin is thought to enhance proteolytic processes enabling tumor cells to invade and metastasize.

Synonym: Tna

Molekulargewicht: 20.7 kDa

UniProt: P43025