BTN3A3 Protein (Fc Tag)

Produktnummer ABIN7317245

Produktdetails

Target: BTN3A3 (butyrophilin, Subfamily 3, Member A3 (BTN3A3))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses BTN3A3 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant Human BTN3A3 Protein (Fc Tag)

Sequenz: Met 1-Trp248

Produktmerkmale: A DNA sequence encoding the human BTN3A3 (O00478-1) (Met1-Trp248) was fused with Fc region of mouse IgG at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: BTN3A3 (butyrophilin, Subfamily 3, Member A3 (BTN3A3))

Andere Bezeichnung: BTN3A3 (BTN3A3 Produkte)

Synonyme: Btn3a3 Protein, EG632126 Protein, NG11 Protein, BTF3 Protein, butyrophilin-like 4 Protein, butyrophilin subfamily 3 member A3 Protein, butyrophilin, subfamily 3, member A3 Protein, Btnl4 Protein, BTN3A3 Protein

Hintergrund:

Background: Tumor necrosis factor receptor superfamily, member 19 (TNFRSF19), also known as TAJ-alpha or TROY, is a member of the TNF-receptor superfamily. TNFRSF19/TROY expression is detected in the pulmonary epithelium and the ductal epithelium of the prostate and parotid glands. TNFRSF19/TROY expression is detected in some adenocarcinoma cell lines that arise from this tissue. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells. TNFRSF19/TROY is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. TNFRSF19/TROY was negatively regulated by adipogenic transcription factor CCAAT/enhancer-binding proteins (C/EBP). TNFRSF19 signals activation of the Jnk pathway and induces cell death. Overexpression of TNFRSF19 also signals NFB activation, comparable and similar to that by p75NGFR. TNFRSF19/TROY is capable of activating key signaling pathways of the TNF receptor family, and its predominant expression patterns suggest that it plays a role in the growth and regulation of epithelial tissues.

Synonym: Butyrophilin subfamily 3 member A3,BTN3A3,BTF3,BTN3.3

Molekulargewicht: 50 kDa