CD147 Protein (mFc Tag)

Produktnummer ABIN7319917

Produktdetails

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses CD147 Protein ist gelabelt mit mFc Tag.

Verwendungszweck: Recombinant Human Basigin/CD147 (C-mFc)

Sequenz: Ala22-His205

Produktmerkmale: Recombinant Human Basigin is produced by our Mammalian expression system and the target gene encoding Ala22-His205 is expressed with a mFc tag at the C-terminus.

Reinheit: >95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Andere Bezeichnung: Basigin/CD147 (BSG Produkte)

Synonyme: EMMPRIN Protein, RPE7 Protein, 5F7 Protein, CD147 Protein, M6 Protein, OK Protein, TCSF Protein, AI115436 Protein, AI325119 Protein, HT-7 Protein, 5A11 Protein, CE9 Protein, HT7 Protein, Ox47R Protein, basignin Protein, wu:fb26a05 Protein, wu:fo98e12 Protein, bsg Protein, prso03 Protein, basigin (Ok blood group) Protein, basigin Protein, basigin (Ok blood group) S homeolog Protein, BSG Protein, Bsg Protein, bsg Protein, bsg.S Protein

Hintergrund:

Background: Basigin/CD147 is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore, CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction. CD147 displays increased expression in many cancers, and it has been previously demonstrated to participate in cancer metastasis and progression.

Synonym: Basigin, Basic immunoglobulin superfamily, HT7 antigen, Membrane glycoprotein gp42, CD147, Bsg

Molekulargewicht: 46.5 kDa

Pathways: S100 Proteine