ALDH1A3 Protein (His tag)

Produktnummer ABIN7319705

Produktdetails

Target: ALDH1A3 (Aldehyde Dehydrogenase 1 Family, Member A3 (ALDH1A3))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses ALDH1A3 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human ALDH1A3 Protein (His Tag)

Sequenz: Met1-Pro512

Produktmerkmale: Recombinant Human ALDH1A3 is produced by our E.coli expression system and the target gene encoding Met1-Pro512 is expressed with a 6His tag at the N-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mMNaCl, pH 7.5,20 % Glycerol.

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Antigendetails

Target: ALDH1A3 (Aldehyde Dehydrogenase 1 Family, Member A3 (ALDH1A3))

Andere Bezeichnung: ALDH1A3 (ALDH1A3 Produkte)

Synonyme: RALDH3 Protein, ALDH1A3 Protein, ALDH1A6 Protein, ALDH6 Protein, MCOP8 Protein, Aldh6 Protein, V1 Protein, aldehyde dehydrogenase 1 family member A3 Protein, aldehyde dehydrogenase 1 family member A3 L homeolog Protein, aldehyde dehydrogenase 1 family, member A3 Protein, aldehyde dehydrogenase family 1, subfamily A3 Protein, ALDH1A3 Protein, aldh1a3.L Protein, aldh1a3 Protein, Aldh1a3 Protein

Hintergrund:

Background: Aldehyde dehydrogenase 1 family member A3 (ALDH1A3), also known as retinaldehyde dehydrogenase 3 (RALDH3), is a member of the aldehyde dehydrogenase family known to metabolize a wide variety of aldehydes. ALDH1A3 specifically oxidizes retinal to retinoic acid (RA) and is differentially expressed in developing embryonic tissues and adult organs. The RA produced by ALDH1A3 in rodents contributes to the development of skin and hair follicles, brain, tooth buds, lungs, olfactory bulbs, kidneys, eyes, skeletal muscle and seminal vesicles. In recent research, ALDH1A3 could be as a marker of cancer stem cell to predict metastasis or clinical prognosis in many cancers.

Synonym: Aldehyde dehydrogenase family 1 member A3, ALDH1A3, Aldehyde dehydrogenase 6, Retinaldehyde dehydrogenase 3, RALDH-3, ALDH6,ALDH1A6,MCOP8,RALDH3

Molekulargewicht: 57.5 kDa

UniProt: P47895

Pathways: Retinoic Acid Receptor Signaling Pathway