ALDH1A2 Protein (His tag)

Produktnummer ABIN7318142

Produktdetails

Target: ALDH1A2 (Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses ALDH1A2 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human ALDH1A2 Protein (His Tag)

Sequenz: Met 1-Ser518

Produktmerkmale: Recombinant Human Aldehyde dehydrogenase family 1 member A2 is produced by our E.coli expression system and the target gene encoding Met1-Ser518 is expressed with a 6His tag at the N-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mMNaCl, pH 7.5,20 % Glycerol.

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Antigendetails

Target: ALDH1A2 (Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2))

Andere Bezeichnung: ALDH1A2 (ALDH1A2 Produkte)

Synonyme: Raldh-2 Protein, RALDH(II) Protein, RALDH2 Protein, RALDH2-T Protein, fb50h01 Protein, raldh2 Protein, AV116159 Protein, Aldh1a7 Protein, Raldh1 Protein, Raldh2 Protein, aldehyde dehydrogenase 1 family, member A2 Protein, aldehyde dehydrogenase 1 family member A2 Protein, aldehyde dehydrogenase family 1, subfamily A2 Protein, Aldh1a2 Protein, ALDH1A2 Protein, aldh1a2 Protein

Hintergrund:

Background: Aldehyde dehydrogenase 1 family member A2 (ALDH1A2), also known as retinaldehyde dehydrogenase 2 (RALDH2), belongs to the aldehyde dehydrogenase family which contains two members, the ALDH1 s (ALDH1A1, ALDH1A2 and ALDH1A3) and the 9-cis retinaldehyde dehydrogenase ALDH8 s. ALDH1A2 is key enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. RA is a paracrine hormone signaling molecule that functions in developing and adult tissues. ALDH1A2 was also found to regulate normal and tumor cell growth and differentiation. Several studies showed that ALDH1A2 expression is increased after the appearance of AraC resistance in clinical cases which means this protein is effective in AraC resistance.

Synonym: Aldehyde dehydrogenase family 1 member A2, Retinaldehyde-specific dehydrogenase type 2, RALDH(II), Retinal dehydrogenase 2, ALDH1A2, RALDH2

Molekulargewicht: 58.2 kDa

UniProt: O94788

Pathways: Retinoic Acid Receptor Signaling Pathway