ART4 Protein (His tag)

Produktnummer ABIN7320048

Produktdetails

Target: ART4 (ADP-Ribosyltransferase 4 (Dombrock Blood Group) (ART4))

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses ART4 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Mouse ART4/CD297 Protein (His Tag)

Sequenz: Met1-Lys 263

Produktmerkmale: A DNA sequence encoding the mature form of mouse ART4 (EDL10575.1) (Met1-Lys 263) was expressed, with a C-terminal polyhistidine tag.

Reinheit: > 92 % as determined by SDS-PAGE

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: ART4 (ADP-Ribosyltransferase 4 (Dombrock Blood Group) (ART4))

Andere Bezeichnung: ART4/CD297 (ART4 Produkte)

Synonyme: ARTC4 Protein, CD297 Protein, DO Protein, DOK1 Protein, ATR4 Protein, 4432404K01Rik Protein, Dombrock Protein, ADP-ribosyltransferase 4 (Dombrock blood group) Protein, ADP-ribosyltransferase 4 Protein, ART4 Protein, Art4 Protein

Hintergrund:

Background: ADP-ribosyltransferase 4 (Dombrock blood group), also known as Mono-ADP-ribosyltransferase 4(ART4), Dombrock blood group carrier molecule and CD297, is a protein that contains a mono-ADP-ribosylation (ART) motif. It is a member of the ADP-ribosyltransferase gene family but enzymatic activity has not been demonstrated experimentally. ADP-ribosyltransferase catalyzes the ADP-ribosylation of arginine residues in proteins. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera, pertussis, and heat-labile enterotoxins of E. coli. ART4 could be detected on HEL cells and erythrocytes by FACS analysis while it was absent from activated monocytes, despite the presence of ART4 mRNA in these cells. ART is also known as the carrier of the Dombrock blood group alloantigens (Do) which is glycosylphosphatidylinosotol-anchored to the erythrocyte membrane.

Synonym: 4432404K01Rik,ARTC4,DO,DOK1

Molekulargewicht: 28.2 kDa