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ASXL1 Protein (GST tag)

ASXL1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7319711
  • Target Alle ASXL1 Proteine anzeigen
    ASXL1 (Additional Sex Combs Like 1 (ASXL1))
    Protein-Typ
    Recombinant
    Spezies
    • 5
    • 1
    Human
    Quelle
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses ASXL1 Protein ist gelabelt mit GST tag.
    Verwendungszweck
    Recombinant Human ASXL1 Protein (GST Tag)
    Sequenz
    Lys1477-Arg154
    Produktmerkmale
    Recombinant Human ASXL1 is produced by our E.coli expression system and the target gene encoding Lys1477-Arg1541 is expressed with a GST tag at the N-terminus.
    Reinheit
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product ASXL1 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    ASXL1 (Additional Sex Combs Like 1 (ASXL1))
    Andere Bezeichnung
    ASXL1 (ASXL1 Produkte)
    Synonyme
    asxl1 Protein, MGC83850 Protein, mKIAA0978 Protein, BOPS Protein, MDS Protein, additional sex combs like 1, transcriptional regulator L homeolog Protein, additional sex combs like 1, transcriptional regulator Protein, additional sex combs like 1 Protein, asxl1.L Protein, ASXL1 Protein, asxl1 Protein, Asxl1 Protein
    Hintergrund

    Background: Putative Polycomb group protein ASXL1 involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG). It acts as coactivator of RARA and RXRA through association with NCOA1. ASXL1 also acts as corepressor through recruitment of KDM1A and CBX5 to target genes in a cell-type specific manner, the function seems to involve differential recruitment of methylated histone H3 to respective promoters.

    Synonym: Putative Polycomb group protein ASXL1, Additional sex combs-like protein 1, ASXL1, KIAA0978,

    Molekulargewicht
    33.6 kDa
    UniProt
    Q8IXJ9
    Pathways
    Retinoic Acid Receptor Signaling Pathway
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