SOSTDC1 Protein (Fc Tag)

Produktnummer ABIN7121439

Produktdetails

Target: SOSTDC1 (Sclerostin Domain Containing 1 (SOSTDC1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses SOSTDC1 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Human USAG-1 Protein, Fc Tag

Sequenz: Phe 24 - Ser 206

Produktmerkmale: Human USAG-1, Fc Tag (US1-H5254) is expressed from human 293 cells (HEK293). It contains AA Phe 24 - Ser 206 (Accession # Q6X4U4-1).

Reinheit: >90 % as determined by SDS-PAGE.

Endotoxin-Niveau: Less than 1.0 EU per μg by the LAL method.

Anwendungsinformationen

Applikationshinweise: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 47.2 kDa. The protein migrates as 45-65 kDa under reducing (R) condition due to glycosylation.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 51 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Antigendetails

Target: SOSTDC1 (Sclerostin Domain Containing 1 (SOSTDC1))

Andere Bezeichnung: USAG-1 (SOSTDC1 Produkte)

Synonyme: SOSTDC1 Protein, zgc:110293 Protein, DKFZp469J0531 Protein, Usag1 Protein, ECTODIN Protein, USAG1 Protein, 0610006G05Rik Protein, Sostl Protein, USAG-1 Protein, Wise Protein, ectodin Protein, WISE Protein, sclerostin domain containing 1 Protein, sclerostin domain containing 1a Protein, SOSTDC1 Protein, sostdc1a Protein, Sostdc1 Protein

Hintergrund: Synonyms: Uterine sensitization-associated gene 1 protein,
Description: USAG1 (uterine sensitization associated gene 1), also known asSOSTDC1 (sclerostin domain-containing 1), Ectodin, is a secreted protein with a glycosylated N-terminus that contains a C-terminal cysteine knot domain. This C-terminal cysteine knot domain is present in numerous growth factors, including TGFβ, NGF, PDGF, vWF, NDP, and mucin-2, and involved in dimerization, receptor binding, and signal transduction. SOSTDC1 negatively regulates BMP signaling during cellular proliferation, differentiation, and apoptosis in several biological processes (such as dentary morphogenesis, embryo implantation in the endo-metrium, and healing of bone fractures) [8]. In addition, SOSTDC1 might also involve cancer development processes through the regulation of the Wnt pathway.

Molekulargewicht: 47.2 kDa