HSV2 gD
(Herpes Simplex Virus Type 2, Glycoprotein D (HSV2 gD))
Protein-Typ
Recombinant
Spezies
Herpes simplex virus type 2
Quelle
HEK-293 Cells
Aufreinigungstag / Konjugat
Dieses HSV2 gD Protein ist gelabelt mit His tag.
Verwendungszweck
HSV-2 (strain HG52) Envelope Glycoprotein D (gD), His Tag (MALS verified)
Sequenz
Lys 26 - Tyr 310
Produktmerkmale
HSV-2 (strain HG52) Envelope Glycoprotein D (gD), His Tag (GLD-V52H4) is expressed from human 293 cells (HEK293). It contains AA Lys 26 - Tyr 310 (Accession # P03172-1).
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 33.7 kDa. The protein migrates as 44-47 kDa under reducing (R) condition due to glycosylation.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Buffer
PBS, pH 7.4
Lagerung
-20 °C
Informationen zur Lagerung
-20°C
Target
HSV2 gD
(Herpes Simplex Virus Type 2, Glycoprotein D (HSV2 gD))
Andere Bezeichnung
HSV-2 (strain HG52) Envelope Glycoprotein D (gD) (HSV2 gD Produkte)
Hintergrund
Synonyms: gD, Description: Herpesvirus infections are widely spread throughout the world population. Herpes simplex virus (HSV) belongs to the α-herpesvirus subfamily. There are two main types of HSV, HSV-1 and HSV-2, which infect humans. HSV-2 mainly causes genital lesions, whereas HSV-1 is involved in both oral and genital infections. Glycoprotein D (gD) is a structural component of the herpes simplex virus type 1 (HSV-1) envelope which is essential for virus entry and fusion with host cells. gD plays an important role by binding to the host receptors such as herpes virus entry mediator (HVEM) and nectin-1, a member of the immunoglobulin (Ig)-like cell adhesion molecules.