Catalase Protein (CAT) (Fc Tag)

Produktnummer ABIN7092847

Produktdetails

Target: Catalase (CAT)

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Catalase Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant mouse CS1 protein with C-terminal human Fc tag

Spezifität: Mouse CS1 (Ser23-Gly224) hFc (Glu99-Ala330)

Produktmerkmale: Extracellular Domain Protein

Aufreinigung: affinity purification

Reinheit: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: Catalase (CAT)

Andere Bezeichnung: CS1 (CAT Produkte)

Synonyme: 2210418N07 Protein, Cas-1 Protein, Cas1 Protein, Cs-1 Protein, CS1 Protein, Cat01 Protein, Catl Protein, fb68a12 Protein, wu:fb68a12 Protein, CAT Protein, CATA Protein, CG6871 Protein, CT21282 Protein, CatA Protein, DMCATHPO Protein, DROCATHPO Protein, Dmel\\CG6871 Protein, U00145 Protein, bs36h11.y1 Protein, cat Protein, GB11648 Protein, catalase Protein, Cat Protein, BA0843 Protein, DKFZp469E0232 Protein, catalase Protein, Catalase Protein, catalase, gene 2 Protein, CAT Protein, Cat Protein, cat Protein, cat.2 Protein, LOC769804 Protein, BA_0843 Protein

Hintergrund: Synonymes: 19A,19A24,4930560D03Rik,CRACC,CS1
Description: Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2 (PubMed:19648922). Mediates natural killer (NK) cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway (By similarity). Positively regulates NK cell functions by a mechanism dependent on the adapter SH2D1B. In addition to heterotypic NK cells-target cells interactions also homotypic interactions between NK cells may contribute to activation. However, in the absence of SH2D1B, inhibits NK cell function. Acts also inhibitory in T-cells (PubMed:19151721). May play a role in lymphocyte adhesion (By similarity). In LPS-activated monocytes negatively regulates production of proinflammatory cytokines (By similarity).[UniProtKB/Swiss-Prot Function]

Molekulargewicht: predicted molecular mass of 48.4 kDa after removal of the signal peptide.The apparent molecular mass of mCS1-hFc is 55-70 kDa due to glycosylation.

UniProt: Q8BHK6

Pathways: Cellular Glucan Metabolic Process, Cell RedoxHomeostasis, Photoperiodism