ILDR2 Protein (AA 21-186) (Fc Tag)
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- Target Alle ILDR2 Produkte
- ILDR2 (Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 21-186
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses ILDR2 Protein ist gelabelt mit Fc Tag.
- Produktmerkmale
- Human ILDR2 Protein, Fc Tag
- Reinheit
- >95 % as determined by SDS-PAGE.
- Endotoxin-Niveau
- Less than 1.0 EU per μg by the LAL method.
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Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2) (AA 21-184) protein (Fc Tag)
ILDR2 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 92 % as determined by HPLC
Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2) protein (His tag)ILDR2 Spezies: Human Wirt: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2) (AA 21-186) protein (His tag)Crystallography grade ILDR2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, Crys, ELISA, WB
Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2) (AA 36-201) protein (His tag)Crystallography grade ILDR2 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, Crys, ELISA, WB
Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2) (AA 208-639) protein (His tag)Crystallography grade ILDR2 Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, Crys, ELISA, WB
Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2) (AA 223-661) protein (His tag)Crystallography grade ILDR2 Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, Crys, ELISA, WB
Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2) (AA 21-639) protein (rho-1D4 tag)Crystallography grade ILDR2 Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, Crys, ELISA, WB
Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2) (AA 36-661) protein (rho-1D4 tag)Crystallography grade ILDR2 Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, Crys, ELISA, WB
Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2) (AA 1-186), (Extracellular) protein (GST tag)ILDR2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % SDS
Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2) (AA 1-186), (Extracellular) protein (His tag)ILDR2 Spezies: Human Wirt: Hefe Recombinant > 90 % SDS
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Lagerung
- -20 °C
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- Target
- ILDR2 (Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2))
- Andere Bezeichnung
- ILDR2 (ILDR2 Produkte)
- Synonyme
- C1orf32 Protein, RP4-782G3.2 Protein, dJ782G3.1 Protein, immunoglobulin like domain containing receptor 2 Protein, ILDR2 Protein
- Hintergrund
- ILDR2 belongs to the immunoglobulin superfamily. May be involved in lipid homeostasis and ER stress pathways. ILDR2 as a novel B7-like protein with robust T cell inhibitory activity, expressed in immune cells and in immune-privileged and inflamed tissues. A fusion protein, consisting of ILDR2 extracellular domain with an Fc fragment, that binds to a putative counterpart on activated T cells showed a beneficial effect in the collagen-induced arthritis model and abrogated the production of proinflammatory cytokines and chemokines in autologous synovial-like cocultures of macrophages and cytokine-stimulated T cells. Collectively, these findings point to ILDR2 as a novel negative regulator for T cells, with potential roles in the development of immune-related diseases, including autoimmunity and cancer.
- Molekulargewicht
- 45.1 kDa
- NCBI Accession
- NP_955383
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