FOLR2 Protein (AA 34-245) (His tag)
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- Target Alle FOLR2 Proteine anzeigen
- FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 34-245
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Spezies
- Cynomolgus
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses FOLR2 Protein ist gelabelt mit His tag.
- Produktmerkmale
- Cynomolgus FOLR2 Protein, His Tag
- Reinheit
- >90 % as determined by SDS-PAGE.
- Endotoxin-Niveau
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product FOLR2 Protein
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Folate Receptor 2 (Fetal) (FOLR2) (AA 17-228) protein (His tag)
FOLR2 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Folate Receptor 2 (Fetal) (FOLR2) (AA 9-187) protein (His tag)FOLR2 Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Folate Receptor 2 (Fetal) (FOLR2) (AA 21-227) protein (His tag)FOLR2 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Folate Receptor 2 (Fetal) (FOLR2) (AA 1-255) protein (GST tag)FOLR2 Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AA, AP
Folate Receptor 2 (Fetal) (FOLR2) (AA 36-128) protein (GST tag)FOLR2 Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AA, AP
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 100 mM Glycine, pH 7.5
- Lagerung
- -20 °C
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- Target
- FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))
- Andere Bezeichnung
- FOLR2 (FOLR2 Produkte)
- Synonyme
- FOLR2 Protein, BETA-HFR Protein, FBP Protein, FBP/PL-1 Protein, FR-BETA Protein, FR-P3 Protein, FBP2 Protein, Folbp-2 Protein, Folbp2 Protein, folate receptor 1 Protein, folate receptor beta Protein, folate receptor 2 (fetal) Protein, FOLR1 Protein, FOLR2 Protein, Folr2 Protein
- Hintergrund
- Folate receptor beta is also known as Folate receptor 2, FBP, FOLR2, BETA-HFR, FBP/PL-1, FR-BETA, FR-P3, and is a member of the folate receptor (FOLR) family. and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68 % and 79 % sequence homology with the FOLR1 and FOLR3 proteins, respectively. The FOLR2 protein was originally thought to exist only in placenta, but is also detected in spleen, bone marrow, and thymus. FOLR2 is predominantly expressed in placenta, cells of the neutrophilic lineage, and some CD34+ hematopoietic progenitor cells. It is upregulated on myeloid leukemias, head and neck squamous cell carcinomas, and several nonepithelial cancers. It is also upregulated on macrophages and monocytes at chronic inflammatory sites including rheumatoid arthritis synovium and glioblastoma. FOLR2 is a marker for macrophages generated in the presence of M-CSF, but not GM-CSF. Its expression correlates with increased folate uptake ability. Folate conjugates of therapeutic drugs are a potential immunotherapy tool to target tumor-associated macrophages.
- Molekulargewicht
- 26.5 kDa
- Pathways
- Dicarboxylic Acid Transport
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