Complement C2 Protein (AA 21-752) (His tag)

Produktnummer ABIN7013389

Produktdetails

Target: Complement C2

Protein-Typ: Recombinant

Proteineigenschaft: AA 21-752

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Complement C2 Protein ist gelabelt mit His tag.

Produktmerkmale: Human Complement Component C2 Protein, His Tag (MALS verified) (active enzyme)

Reinheit: >90 % as determined by SDS-PAGE.

Endotoxin-Niveau: Less than 1.0 EU per μg by the LAL method.

Anwendungsinformationen

Applikationshinweise: MALS verified

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 20 mM Tris, 150 mM NaCl, pH 7.5

Lagerung: -20 °C

Antigendetails

Target: Complement C2

Andere Bezeichnung: Complement Component C2 (Complement C2 Produkte)

Synonyme: CO2 Protein, complement C2 Protein, complement component 2 (within H-2S) Protein, C2 Protein

Hintergrund: C2 is a major histocompatibility complex class-III protein. Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase. The lectin (LP) and classical (CP) pathways are two of the three main activation cascades of the complement system. These pathways start with recognition of different pathogen- or danger-associated molecular patterns and include identical steps of proteolytic activation of complement component C4, formation of the C3 proconvertase C4b2, followed by cleavage of complement component C2 within C4b2 resulting in the C3 convertase C4b2a.

Molekulargewicht: 83.0 kDa

NCBI Accession: NP_000054