Secretory Component Protein (AA 19-603) (Twin-Strep tag)

Produktnummer ABIN7013229

Produktdetails

Target: Secretory Component

Protein-Typ: Recombinant

Proteineigenschaft: AA 19-603

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Secretory Component Protein ist gelabelt mit Twin-Strep tag.

Verwendungszweck: Human Secretory Component, Twin Strep Tag

Reinheit: >90 % as determined by SDS-PAGE.

Endotoxin-Niveau: Less than 1.0 EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.3

Lagerung: -20 °C

Antigendetails

Target: Secretory Component

Abstract: Secretory Component Produkte

Synonyme: RNPIGR2 Protein, pIgA-R Protein, polymeric immunoglobulin receptor Protein, PIGR Protein, Pigr Protein

Hintergrund: The secretory component (SC) is a unique polypeptide chain that may be found in immunoglobulins A and M (IgA and IgM). The SC wraps around two IgA units joined by a J chain protein fragment, resulting in a configuration with each of the two antigen binding regions of the two constituent y-shaped antibodies exposed. One identified function of secretory components is to protect IgA antibodies from degradation by the gastric acids and enzymes of the digestive system. It also appears that SC may serve in the three-dimensional organization or in the transport and distribution of the resulting IgA complexes.

Molekulargewicht: 67.6 kDa

NCBI Accession: NP_002635