IL-2 R beta & IL-2 R alpha & IL-2 R gamma (AA 27-239) (Active) protein (His tag,Twin-Strep tag)

Produktnummer ABIN7013080

Produktdetails

Target: IL-2 R beta & IL-2 R alpha & IL-2 R gamma

Protein-Typ: Recombinant

Biologische Aktivität: Active

Proteineigenschaft: AA 27-239

Spezies: Ratte

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: His tag,Twin-Strep tag

Verwendungszweck: Rat IL-2 R beta&IL-2 R alpha&IL-2 R gamma Protein, His Tag&Twin-Strep Tag (MALS verified)

Reinheit: >95 % as determined by reduced SDS-PAGE.

Endotoxin-Niveau: Less than 1.0 EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4

Lagerung: -20 °C

Antigendetails

Target: IL-2 R beta & IL-2 R alpha & IL-2 R gamma

Hintergrund: Both Interleukin-2 receptor subunit beta and Interleukin-2 receptor subunit gamma are receptor for interleukin-2. Common subunit for the receptors for a variety of interleukins. Interacts with SHB upon interleukin stimulation. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.

Molekulargewicht: 30.2 kDa & 59.3 kDa