PVRIG Protein (AA 41-171) (Fc Tag,AVI tag,Biotin)

Produktnummer ABIN6973209

Produktdetails

Target: PVRIG (Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Proteineigenschaft: AA 41-171

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PVRIG Protein ist gelabelt mit Fc Tag,AVI tag,Biotin.

Spezifität: Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.

Produktmerkmale: Biotinylated Human PVRIG Protein, Fc,Avitag™ (HPLC verified)

Reinheit: >90 % as determined by SDS-PAGE.

Endotoxin-Niveau: Less than 1.0 EU per μg by the LAL method.

Anwendungsinformationen

Applikationshinweise: HPLC verified

Kommentare:

Ready-to-use Avitag™ biotinylated protein:
The product is exclusively produced using the Avitag™ technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS,  pH 7.4

Lagerung: -20 °C

Antigendetails

Target: PVRIG (Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG))

Andere Bezeichnung: PVRIG (PVRIG Produkte)

Synonyme: C7orf15 Protein, PVR related immunoglobulin domain containing Protein, PVRIG Protein

Hintergrund: Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34  kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain. Notably, the intracellular domain of phatases. The extracellular domain sequence of human and mouse CD112R have 65.3 % similarity. CD112R may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.

Molekulargewicht: 41.9 kDa

NCBI Accession: NP_076975