MMP11 Protein (Fc Tag)

Produktnummer ABIN6964295

Produktdetails

Target: MMP11 (Matrix Metallopeptidase 11 (Stromelysin 3) (MMP11))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses MMP11 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant human MMP11 protein with C-terminal human Fc tag

Spezifität: MMP11 (Arg32-Leu488) hFc (Glu99-Ala330)

Produktmerkmale: Extracellular Domain Protein

Aufreinigung: affinity purification

Reinheit: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Konservierungsmittel: Without preservative

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: MMP11 (Matrix Metallopeptidase 11 (Stromelysin 3) (MMP11))

Andere Bezeichnung: MMP11 (MMP11 Produkte)

Synonyme: SL-3 Protein, ST3 Protein, STMY3 Protein, Stmy3 Protein, MMP-11 Protein, matrix metallopeptidase 11 Protein, matrix metallopeptidase 11 L homeolog Protein, stromelysin-3 Protein, MMP11 Protein, Mmp11 Protein, mmp11.L Protein, LOC103694874 Protein

Hintergrund: Synonymes: SL-3, ST3, STMY3
Description: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq, Jul 2008]

Molekulargewicht: predicted molecular mass of 76.5 kDa after removal of the signal peptide.The apparent molecular mass of MMP11-hFc is 70-100 kDa due to glycosylation.

UniProt: P24347