Claudin 3 Protein (CLDN3) (Fc Tag)

Produktnummer ABIN6964182

Produktdetails

Target: Claudin 3 (CLDN3)

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Claudin 3 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant human CLDN3 protein with C-terminal human Fc tag

Spezifität: CLDN3 (Arg30-Arg80) hFc (Glu99-Ala330)

Produktmerkmale: Extracellular Domain Protein

Aufreinigung: affinity purification

Reinheit: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Konservierungsmittel: Without preservative

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: Claudin 3 (CLDN3)

Andere Bezeichnung: CLDN3 (CLDN3 Produkte)

Synonyme: claudin-3 Protein, cpe-r2 Protein, cpetr2 Protein, hrvp1 Protein, rvp1 Protein, CLDN3 Protein, LOC100228090 Protein, C7orf1 Protein, CPE-R2 Protein, CPETR2 Protein, HRVP1 Protein, RVP1 Protein, AI182374 Protein, Cpetr2 Protein, mRVP1 Protein, claudin 3 L homeolog Protein, claudin 3 Protein, claudin-4-like Protein, cldn3.L Protein, cldn3 Protein, CLDN3 Protein, LOC100228090 Protein, Cldn3 Protein

Hintergrund: Synonymes: C7orf1, CPE-R2, CPETR2, HRVP1, RVP1
Description: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.

Molekulargewicht: predicted molecular mass of 31.8 kDa after removal of the signal peptide. The apparent molecular mass of CLDN3-hFc is 35-40 kDa due to glycosylation.

UniProt: O15551

Pathways: Hepatitis C