CD51 Protein (Fc Tag)

Produktnummer ABIN6964181

Produktdetails

Target: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CD51 Protein ist gelabelt mit Fc Tag.

Sequenz: ITGAV(Phe31-Val992)+ ITGB1(Gln21-Asp728)+hFc(Glu99-Ala330)

Produktmerkmale: Tagged Protein: C-Human Fc tag

Aufreinigung: affinity purification

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Konservierungsmittel: Without preservative

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C for 12 months (Avoid repeated freezing and thawing)

Haltbarkeit: 12 months

Antigendetails

Target: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Andere Bezeichnung: ITGAV (ITGAV Produkte)

Synonyme: 1110004F14Rik Protein, 2610028E01Rik Protein, CD51 Protein, D430040G12Rik Protein, MSK8 Protein, VNRA Protein, VTNR Protein, Cd51 Protein, integrin subunit alpha V Protein, integrin alpha V Protein, ITGAV Protein, Itgav Protein

Hintergrund: Synonymes: CD51, MSK8, VNRA, VTNR
Description: The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.

Molekulargewicht: 131.34 kDa

UniProt: P06756

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex