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TNF alpha Protein (Tumor Necrosis Factor alpha) (His tag)

TNF alpha Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 %
Produktnummer ABIN6961133
$553.85
Zzgl. Versandkosten $45.00
Lieferung in 9 bis 11 Werktagen
  • Target Alle TNF alpha Proteine anzeigen
    TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
    Protein-Typ
    Recombinant
    Spezies
    • 34
    • 21
    • 9
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 51
    • 26
    • 13
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses TNF alpha Protein ist gelabelt mit His tag.
    Sequenz
    TNFα(Val77-Leu233)+6xHis tag
    Produktmerkmale
    Tagged Protein: C-6xHis tag
    Aufreinigung
    affinity purification
    Reinheit
    > 95 %
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C for 12 months (Avoid repeated freezing and thawing)
  • Target
    TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
    Andere Bezeichnung
    TNFalpha (TNF alpha Produkte)
    Synonyme
    DIF, TNF-alpha, TNFA, TNFSF2, RATTNF, Tnfa, tnf, TNF-a, TNFalpha, Tnfsf1a, TNFa, cTNF, Tnf-alpha, tnfa-like, TNF-ALPHA, dif, tnfa, xtnf, tnfsf2, tnf-alpha, Cachectin, tumor necrosis factor, tumor necrosis factor b (TNF superfamily, member 2), tumor necrosis factor alpha, tumor necrosis factor a (TNF superfamily, member 2), TNF, Tnf, tnf, tnfb, tnf-alpha, LOC103694380, tnfa
    Hintergrund
    Synonymes: DIF,TNF-alpha,TNFA,TNFSF2,cachexin,cachectin,TNFα
    Description: This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
    Molekulargewicht
    18.1 kDa
    Gen-ID
    7124
    UniProt
    P01375
    Pathways
    NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, TLR Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome
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