SARS-Coronavirus Nonstructural Protein 8 (SARS-CoV NSP8)
Protein-Typ
Recombinant
Spezies
SARS Coronavirus-2 (SARS-CoV-2)
Quelle
Escherichia coli (E. coli)
Aufreinigungstag / Konjugat
His tag
Applikation
SDS-PAGE (SDS)
Verwendungszweck
SARS-CoV-2 (COVID-19) NSP8 Protein, His Tag
Sequenz
AA 1-198
Produktmerkmale
SARS-CoV-2 NSP8, His Tag (NS8-C5149) is expressed from E.coli cells. It contains AA Ala 1 - Gln 198 (Accession # YP_009725304.1).Predicted N-terminus: Met This protein carries a polyhistidine tag at the N-terminus.
pp1a Protein, pp1ab Protein, orf1ab polyprotein (pp1ab) Protein, orf1ab Protein
Substanzklasse
Viral Protein
Hintergrund
NSP8, forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers. To ultimately combat the emerging COVID-19 pandemic, it is desired to develop an effective and safe vaccine against this highly contagious disease caused by the SARS-CoV-2 coronavirus. By investigating the entire proteome of SARS-CoV-2, six proteins, including the S protein and five non-structural proteins (nsp3, 3CL-pro, and nsp8-10) were predicted to be adhesins, which are crucial to the viral adhering and host invasion. The S, nsp3, and nsp8 proteins were also predicted by Vaxign-ML to induce high protective antigenicity.