MNDA Protein (AA 1-407) (His tag)

Produktnummer ABIN668050

Produktdetails

Target: MNDA (Myeloid Cell Nuclear Differentiation Antigen (MNDA))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-407

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses MNDA Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: MNDA, 1-407aa, Human, His tag, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.1 M NaCl.

Lagerung: 4 °C

Antigendetails

Target: MNDA (Myeloid Cell Nuclear Differentiation Antigen (MNDA))

Andere Bezeichnung: MNDA (MNDA Produkte)

Synonyme: PYHIN3 Protein, A730048F03 Protein, Ifi205b Protein, myeloid cell nuclear differentiation antigen Protein, interferon activated gene 211 Protein, MNDA Protein, Ifi211 Protein

Hintergrund: MNDA, also known as myeloid cell nuclear differentiation antigen, is detected only in nuclei of cells of the granulocyte-monocyte lineage. This protein may act as a transcriptional activator/repressor in the myeloid lineage and plays a role in the granulocyte/monocyte cell-specific response to interferon. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. Recombinant MNDA protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: PYHIN3, Myeloid cell nuclear differentiation antigen. NCBI no.: NP_002423

Molekulargewicht: 47.9 kDa (427aa), confirmed by MALDI-TOF.