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IMPDH2 Protein (AA 1-514) (His tag)

IMPDH2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Produktnummer ABIN667973
  • Target Alle IMPDH2 Proteine anzeigen
    IMPDH2 (IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 1-514
    Spezies
    • 6
    • 1
    • 1
    Human
    Quelle
    • 3
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses IMPDH2 Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Produktmerkmale
    IMPDH2, 1-514aa, Human, His tag, E.coli
    Reinheit
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product IMPDH2 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 150mM NaCl
    Lagerung
    4 °C
  • Target
    IMPDH2 (IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))
    Andere Bezeichnung
    IMPDH2 (IMPDH2 Produkte)
    Synonyme
    imp2 Protein, impd2 Protein, impdh-ii Protein, impdh2 Protein, IMPD2 Protein, IMPDH-II Protein, IMPD 2 Protein, IMPDH 2 Protein, cb635 Protein, wu:fb64g02 Protein, wu:fc43f09 Protein, IMPD Protein, inosine monophosphate dehydrogenase 2 Protein, IMP (inosine 5'-monophosphate) dehydrogenase 2 Protein, inosine 5'-phosphate dehydrogenase 2 Protein, IMPDH2 Protein, impdh2.S Protein, impdh2 Protein, Impdh2 Protein
    Hintergrund
    IMPDH2 belongs to the IMPDH/GMPR family. It catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. IMPDH2 is the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. Also IMPDH1 and IMPDH2 are targets for the important immunosuppressive drug, mycophenolic acid (MPA). Recombinant human IMPDH2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Inosine-5'-monophosphate dehydrogenase 2, IMPD2, IMPDH-II. NCBI no.: NP_000875
    Molekulargewicht
    58.0kDa (534aa)
    Pathways
    Ribonucleoside Biosynthetic Process, SARS-CoV-2 Protein Interaktom
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