ABO Protein (AA 54-354) (His tag)

Produktnummer ABIN667951

Produktdetails

Target: ABO (Histo-blood group A transferase (ABO))

Protein-Typ: Recombinant

Proteineigenschaft: AA 54-354

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses ABO Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: ABO, 54-354aa, Human, His tag, E.coli

Reinheit: > 85 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 200mM NaCl

Lagerung: 4 °C

Antigendetails

Target: ABO (Histo-blood group A transferase (ABO))

Andere Bezeichnung: ABO (ABO Produkte)

Synonyme: A3GALNT Protein, A3GALT1 Protein, GTB Protein, NAGAT Protein, ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Protein, ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase, transferase B, alpha 1-3-galactosyltransferase) Protein, ABO Protein, Abo Protein

Hintergrund: ABO, also known as NAGAT, belongs to the glycosyltransferase 6 family. This protein is the basis of the ABO blood group system and related to the first discovered blood group system, ABO. Which allele is present in an individual determines the blood group. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. Recombinant human ABO protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Histo-blood group ABO system transferase, A3GALNT, A3GALT1, GTB, NAGAT. NCBI no.: NP_065202

Molekulargewicht: 37.4kDa (322aa), confirmed by MALDI-TOF