MYLPF Protein (AA 1-169) (His tag)

Produktnummer ABIN667922

Produktdetails

Target: MYLPF (Myosin Light Chain, phosphorylatable, Fast Skeletal Muscle (MYLPF))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-169

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses MYLPF Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: MYLPF, 1-169aa, Human, His tag, E.coli

Reinheit: > 85 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 100mM NaCl

Lagerung: 4 °C

Antigendetails

Target: MYLPF (Myosin Light Chain, phosphorylatable, Fast Skeletal Muscle (MYLPF))

Andere Bezeichnung: MYLPF (MYLPF Produkte)

Synonyme: 2410014J02Rik Protein, MLC-2 Protein, Mlc2 Protein, MLC2 Protein, Myl2 Protein, Myolc1 Protein, HUMMLC2B Protein, MRLC2 Protein, MYL11 Protein, SkMLC Protein, DTNB Protein, G2 Protein, LC2f Protein, MYLPF Protein, cb46 Protein, mlc2f Protein, mylz2 Protein, sb:cb46 Protein, zgc:103639 Protein, myosin light chain, phosphorylatable, fast skeletal muscle Protein, myosin light chain, phosphorylatable, fast skeletal muscle L homeolog Protein, myosin light chain, phosphorylatable, fast skeletal muscle a Protein, myosin light chain, phosphorylatable, fast skeletal muscle b Protein, Mylpf Protein, MYLPF Protein, mylpf.L Protein, mylpfa Protein, mylpfb Protein

Hintergrund: Myosin regulatory light chains, including MRCL3, MYLPF and MYL9, regulate contraction in smooth muscle and non-muscle cells via phosphorylation by myosin light chain kinase (MLCK). Phosphorylation of myosin regulatory light chains, catalyzed by MLCK in the presence of calcium and calmodulin, increases the actin-activated myosin ATPase activity, thereby regulating the contractile activity. MYLPF is critically important for fast and slow skeletal muscle development. Recombinant human MYLPF protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Myosin regulatory light chain 2, skeletal muscle isoform, MRLC2, MYL11, Fast skeletal myosin light chain 2, MLC2B. NCBI no.: NP_037424

Molekulargewicht: 21.2kDa (189aa), confirmed by MALDI-TOF

Pathways: Myometrial Relaxation and Contraction