RNMT Protein (AA 1-476) (His tag)

Produktnummer ABIN7279447

Produktdetails

Target: RNMT (RNA Guanine-7 Methyltransferase (RNMT))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-476

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses RNMT Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: RNMT, 1-476aa, Human, His tag, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 100mM NaCl

Lagerung: 4 °C

Antigendetails

Target: RNMT (RNA Guanine-7 Methyltransferase (RNMT))

Andere Bezeichnung: RNMT (RNMT Produkte)

Synonyme: xCMT1 Protein, MET Protein, RG7MT1 Protein, hCMT1c Protein, 2610002P10Rik Protein, AI848273 Protein, Rg7mt1 Protein, mKIAA0398 Protein, rnmt Protein, im:6910566 Protein, wu:fi09c12 Protein, RNA (guanine-7-) methyltransferase L homeolog Protein, RNA guanine-7 methyltransferase Protein, RNA (guanine-7-) methyltransferase Protein, rnmt.L Protein, RNMT Protein, Rnmt Protein, rnmt Protein

Hintergrund: RNMT (mRNA cap guanine-N7 methyltransferase), also known as MET, RG7MT1 or hCMT1c, is a widely expressed nuclear protein that belongs to the mRNA cap methyltransferase family. Cap-dependent mRNA translation requires the methylation of the mRNA guanosine cap by RNMT. RNMT catalyzes the transfer of a methyl group from AdoMet (S-adenosylmethionine) to the GpppN end of the growing mRNA at the N-7 position, thereby producing AdoHyc (S-adenosylhomocysteine) and m7GpppN terminated RNA. Recombinant human RNMT protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: mRNA cap guanine-N7 methyltransferase, MET, RG7MT1, DKFZp686H1252, EC 2.1.1.56, hcm1p, hCMT1, HCMT1a, hCMT1c, hMet, hypothetical protein KIAA0396, KIAA0398, MET, mRNA (guanine 7)methyltransferase, mRNA (guanine N(7)) methyltransferase, mRNA cap methyltransferase, OTTHUMP00000162509, RNA guanine 7 methyltransferase, RNA guanine-7-methyltransferase, RNMT. NCBI no.: NP_003790

Molekulargewicht: 57.0kDa (496aa)