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DDIT4 Protein (AA 1-232) (His tag)

DDIT4 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Produktnummer ABIN667871
  • Target Alle DDIT4 Proteine anzeigen
    DDIT4 (DNA-Damage-Inducible Transcript 4 (DDIT4))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 1-232
    Spezies
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 4
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses DDIT4 Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Produktmerkmale
    DDIT4, 1-232aa, Human, His tag, E.coli
    Reinheit
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product DDIT4 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 5mM DTT, 1mM EDTA, 30% glycerol
    Lagerung
    4 °C
  • Target
    DDIT4 (DNA-Damage-Inducible Transcript 4 (DDIT4))
    Andere Bezeichnung
    DDIT4 (DDIT4 Produkte)
    Synonyme
    redd1 Protein, Dig2 Protein, REDD-1 Protein, REDD1 Protein, 5830413E08Rik Protein, AA415483 Protein, Rtp801 Protein, dig2 Protein, rtp801 Protein, sb:cb821 Protein, zgc:64114 Protein, DNA damage inducible transcript 4 Protein, DNA-damage-inducible transcript 4 Protein, DNA damage inducible transcript 4 S homeolog Protein, ddit4 Protein, DDIT4 Protein, Ddit4 Protein, ddit4.S Protein
    Hintergrund
    DDIT4, also known as Dig2 or REDD1, is thought to have function in the regulation of reactive oxygen species. In response to stress due to DNA damage and glucocorticoid treatment, DDIT4 is upregulated at the transcriptional level. DDIT4 negatively regulates the mammalian target of Rapamycin, a serine/threonine kinase often referred to as mTOR. It is crucial in the coupling of extra- and intracellular cues to mTOR regulation. Recombinant human DDIT4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: DNA damage-inducible transcript 4 protein, Dig2, FLJ20500, REDD1, RP11-442H21.1, RTP801. NCBI no.: NP_061931
    Molekulargewicht
    27.5 kDa (252aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
    Pathways
    Neurotrophin Signalübertragung, Regulation of Carbohydrate Metabolic Process
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