UBE2K Protein (AA 1-200) (His tag)

Produktnummer ABIN7279311

Produktdetails

Target: UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-200

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses UBE2K Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: UBE2K, 1-200aa, Human, His tag, E.coli

Reinheit: > 95 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 7.5) containing 1mM DTT, 10% glycerol, 50mM NaCl

Lagerung: 4 °C

Antigendetails

Target: UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

Andere Bezeichnung: UBE2K (UBE2K Produkte)

Synonyme: E2-25K Protein, HIP2 Protein, HYPG Protein, LIG Protein, UBC1 Protein, E2-25k Protein, Hip2 Protein, Hypg Protein, Lig Protein, e2-25k Protein, hip2 Protein, hypg Protein, lig Protein, AW492011 Protein, D5Ertd601e Protein, ube2k Protein, zgc:103472 Protein, zgc:110791 Protein, ubiquitin conjugating enzyme E2 K Protein, ubiquitin-conjugating enzyme E2K Protein, ubiquitin conjugating enzyme E2 K S homeolog Protein, ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast) Protein, ubiquitin-conjugating enzyme E2Ka (UBC1 homolog, yeast) Protein, UBE2K Protein, Ube2k Protein, ube2k.S Protein, ube2k Protein, ube2kb Protein, ube2ka Protein

Hintergrund: Ubiquitin-conjugating enzyme E2 K isoform 1, also known as UBE2K, is a member of the ubiquitin-conjugating enzymes family. These enzymes participate in a variety of cellular processes, including selective protein degradation, DNA repair, cell cycle control, and sporulation. In this mechanism, the ATP-coupled activation and subsequent ligation of ubiquitin are catalyzed by separate enzymes functionally linked by ubiquitin carrier protein UBC1. Also, UBE2K is reportedly involved in Alzheimer's disease, Huntington's disease and antigen processing through its interaction with amyloid-beta, huntingtin, and MHC-heavy chain proteins. Recombinant human UBE2K protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Ubiquitin-conjugating enzyme E2 K isoform 1, HIP2, HYPG, LIG. NCBI no.: NP_005330

Molekulargewicht: 26.5 kDa (236aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)