PTRH2 Protein (AA 64-179) (His tag)

Produktnummer ABIN667850

Produktdetails

Target: PTRH2 (Peptidyl-tRNA Hydrolase 2 (PTRH2))

Protein-Typ: Recombinant

Proteineigenschaft: AA 64-179

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses PTRH2 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: PTRH2, 64-179aa, Human, His tag, E.coli

Reinheit: > 95 % by SDS- PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris buffer (pH 8.0) containing 10% glycerol, 1mM DTT

Lagerung: 4 °C

Antigendetails

Target: PTRH2 (Peptidyl-tRNA Hydrolase 2 (PTRH2))

Andere Bezeichnung: PTRH2 (PTRH2 Produkte)

Synonyme: BIT1 Protein, PTH2 Protein, A230072I16Rik Protein, Bit1 Protein, CGI-147 Protein, wu:fj09f02 Protein, zgc:109954 Protein, RGD1306819 Protein, peptidyl-tRNA hydrolase 2 Protein, ptrh2 Protein, CC1G_10259 Protein, ANI_1_1036184 Protein, AOR_1_2082154 Protein, PTRH2 Protein, Ptrh2 Protein

Hintergrund: PTRH2 (peptidyl-tRNA hydrolase 2), also known as BIT1, is a mitochondrial protein. During apoptosis, PTRH2 is released from the mitochondria to the cytoplasm. Once in the cytoplasm, PTRH2 regulates the function of two transcriptional regulators, TLE5 and TLE1, thereby promoting caspase-independent cell death. The natural substrate for PTRH2 may be petidyl-tRNAs which drop off the ribosome during protein synthesis. Recombinant human PTRH2 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Peptidyl-tRNA hydrolase 2, BIT1, PTH2, CGI-147, Bcl-2 inhibitor of transcription 1. NCBI no.: NP_057161

Molekulargewicht: 14.9 kDa (137aa), confirmed by MALDI-TOF