SNRPF Protein (AA 1-86) (His tag)

Produktnummer ABIN667847

Produktdetails

Target: SNRPF (Small Nuclear Ribonucleoprotein Polypeptide F (SNRPF))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-86

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses SNRPF Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: SNRPF, 1-86aa, Human, His tag, E.coli

Reinheit: > 95 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 1mM EDTA

Lagerung: 4 °C

Antigendetails

Target: SNRPF (Small Nuclear Ribonucleoprotein Polypeptide F (SNRPF))

Andere Bezeichnung: SNRPF (SNRPF Produkte)

Synonyme: BcDNA:GM23968 Protein, CG16792 Protein, Deb Protein, Deb-B Protein, DebB Protein, Dmel\\CG16792 Protein, dF Protein, deb-b Protein, snRNP-F Protein, sm-f Protein, smf Protein, snrpfl Protein, SMF Protein, Sm-F Protein, SmF Protein, 2010013O18Rik Protein, sm-F Protein, Small ribonucleoprotein particle protein SmF Protein, small nuclear ribonucleoprotein polypeptide F Protein, small nuclear ribonucleoprotein polypeptide F S homeolog Protein, SmF Protein, SNRPF Protein, snrpf Protein, Snrpf Protein, snrpf.S Protein

Hintergrund: Small nuclear ribonucleoprotein polypeptide F, also known SNRPF, belongs to the snRNP Sm proteins family. There are at least seven isoforms, E, F, G, D1, D2, D3 and B/B. This class of common proteins plays an essential role in the biogenesis of the snRNPs. In addition, these proteins represent the major targets for the so-called anti-Sm auto-antibodies which are diagnostic for systemic lupus erythematosus (SLE). SNRPF aid in the cytoplasmic construction of the UsnRNPs by binding to aconserved Sm site on UsnRNA and forming a stable snRNP core complex. Recombinant human SNRPF protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Small nuclear ribonucleoprotein polypeptide F, Sm-F, SMF, PBSCF. NCBI no.: NP_003086

Molekulargewicht: 11.8 kDa (106aa), confirmed by MALDI-TOF

Pathways: Ribonucleoprotein Complex Subunit Organization