PYCR1 Protein (AA 1-319) (His tag)

Produktnummer ABIN667842

Produktdetails

Target: PYCR1 (Pyrroline-5-Carboxylate Reductase 1 (PYCR1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-319

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses PYCR1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: PYCR1, 1-319aa, Human, His tag, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl Buffer (pH 8.5) containing 10% Glycerol

Lagerung: 4 °C

Antigendetails

Target: PYCR1 (Pyrroline-5-Carboxylate Reductase 1 (PYCR1))

Andere Bezeichnung: PYCR1 (PYCR1 Produkte)

Synonyme: arcl2b Protein, p5c Protein, p5cr Protein, pig45 Protein, pp222 Protein, pro3 Protein, pycr Protein, ARCL2B Protein, ARCL3B Protein, P5C Protein, P5CR Protein, PIG45 Protein, PP222 Protein, PRO3 Protein, PYCR Protein, zgc:73112 Protein, pyrroline-5-carboxylate reductase family, member 1 L homeolog Protein, pyrroline-5-carboxylate reductase 1 Protein, pyrroline-5-carboxylate reductase 1a Protein, pycr1.L Protein, PYCR1 Protein, Pycr1 Protein, pycr1a Protein

Hintergrund: PYCR1 is a universal housekeeping enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. It forms a homopolymer and localizes to the mitochondrion. Defects in PYCR1 are the cause of cutis laxa autosomal recessive type 2B (ARCL2B). Recombinant human PYCR1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Pyrroline-5-carboxylate reductase 1, ARCL2B, P5C, P5CR, PIG45, PP222, PRO3. NCBI no.: NP_008838

Molekulargewicht: 35.5 kDa(339aa), confirmed by MALDI-TOF