HAGH Protein (AA 1-260) (His tag)

Produktnummer ABIN667841

Produktdetails

Target: HAGH (Hydroxyacylglutathione Hydrolase (HAGH))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-260

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses HAGH Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: HAGH, 1-260aa, Human, His tag, E.coli

Reinheit: > 95 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl Buffer (pH 8.5) containing 10% Glycerol

Lagerung: 4 °C

Antigendetails

Target: HAGH (Hydroxyacylglutathione Hydrolase (HAGH))

Andere Bezeichnung: HAGH (HAGH Produkte)

Synonyme: glo-2 Protein, glo2 Protein, glx2 Protein, glxii Protein, hagh1 Protein, DDBDRAFT_0186675 Protein, DDBDRAFT_0230988 Protein, DDB_0186675 Protein, DDB_0230988 Protein, DDBDRAFT_0183924 Protein, DDBDRAFT_0230991 Protein, DDB_0183924 Protein, DDB_0230991 Protein, BC019817 Protein, Glo-2 Protein, Glo2 Protein, Rsp29 Protein, RSP29 Protein, fa66a03 Protein, wu:fa66a03 Protein, zgc:73161 Protein, GLO2 Protein, GLX2 Protein, GLXII Protein, HAGH1 Protein, hydroxyacylglutathione hydrolase L homeolog Protein, hydroxyacylglutathione hydrolase Protein, beta-lactamase domain-containing protein Protein, hydroxyacyl glutathione hydrolase Protein, hagh.L Protein, CND02510 Protein, gloB1 Protein, gloB2 Protein, Fbal_1466 Protein, Hagh Protein, hagh Protein, HAGH Protein

Hintergrund: HAGH is a member of the glyoxalase family and a thiolesterase which hydrolyses S-lactoyl-glutathione to reduced glutathione and D-lactate. This protein is a detoxifying enzyme of glycolysis byproduct methylglyoxal and a target of p63 and p73 and serves as a pro-survival factor of the p53 family. It exists only as a monomer and binds two zinc ions per subunit. Recombinant human HAGH protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Hydroxyacylglutathione hydrolase, GLO, GLX2, Glyoxalase II, HAGH1. NCBI no.: NP_001035517

Molekulargewicht: 31.4 kDa (284aa), confirmed by MALDI-TOF