HSPB8 Protein (AA 1-196) (His tag)

Produktnummer ABIN667769

Produktdetails

Target: HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-196

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses HSPB8 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: HSPB8/HSP22, 1-196aa, Human, His tag, E.coli

Reinheit: > 95 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 100mM NaCl, 10% glycerol

Lagerung: 4 °C

Antigendetails

Target: HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

Andere Bezeichnung: HSPB8/HSP22 (HSPB8 Produkte)

Synonyme: CMT2L Protein, DHMN2 Protein, E2IG1 Protein, H11 Protein, HMN2 Protein, HMN2A Protein, HSP22 Protein, MGC64408 Protein, hsc70 Protein, wu:fb01g06 Protein, wu:fi48b06 Protein, fc09c11 Protein, wu:fc04b04 Protein, wu:fc09c11 Protein, zgc:64202 Protein, AU018630 Protein, AW413033 Protein, Cryac Protein, D5Ucla4 Protein, H11K Protein, HSP20-like Protein, Hsp22 Protein, heat shock protein family B (small) member 8 Protein, heat shock protein family B (small) member 8 L homeolog Protein, heat shock protein 8 Protein, heat shock protein b8 Protein, HSPB8 Protein, hspb8.L Protein, hspa8 Protein, hspb8 Protein, Hspb8 Protein

Hintergrund: Heat shock protein beta-8 (HSPB8), also known as HSP22, member of the small heat shock protein superfamily. HSPB8 is predominantly transcribed in skeletal muscle and heart. The chaperone-like activity is of great importance to the function of HSPB8 in various processes including proliferation, apoptosis and macroautophagy. Mutations in the HSPB8 gene are associated with the inherited peripheral neuropathies, autosomal dominant distal hereditary motor neuropathy type IIA (dSMA) and axonal Charcot-Marie-Tooth disease type 2L (CMT2L). Recombinant human HSPB8, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: CRYAC, E2IG1, CMT2L, DHMN2, HMN2, HMN2A, Heat shock protein beta-8, heat shock 22kDa protein 8, H11, HSP22, HspB8. NCBI no.: NP_055180

Molekulargewicht: 23.7 kDa (216aa), confirmed by MALDI-TOF.