Frataxin Protein (FXN) (AA 42-210) (His tag)

Produktnummer ABIN667758

Produktdetails

Target: Frataxin (FXN)

Protein-Typ: Recombinant

Proteineigenschaft: AA 42-210

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses Frataxin Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: Frataxin, 42-210aa, Human, His tag, E.coli

Reinheit: > 95 % by SDS-PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.1 M NaCl.

Lagerung: 4 °C

Antigendetails

Target: Frataxin (FXN)

Andere Bezeichnung: Frataxin (FXN Produkte)

Synonyme: zgc:158218 Protein, LOC100284365 Protein, BcDNA:AT09528 Protein, CG8971 Protein, DFH Protein, Dfh Protein, Dmel\\CG8971 Protein, X25 Protein, dfh Protein, CyaY Protein, FA Protein, FARR Protein, FRDA Protein, RGD1565754 Protein, Frda Protein, frataxin Protein, fxn Protein, LOC100284365 Protein, TVAG_182150 Protein, fh Protein, FTX1 Protein, FXN Protein, Fxn Protein

Hintergrund: Frataxin, also known as FXN, is an iron binding protein which belongs to FRATAXIN family. It is an anti-apoptotic protein which prevents mitochondrial damage, reactive oxygen species production and act as either an iron chaperone or an iron storage protein. Frataxin is localized to the mitochondrion and regulating mitochondrial iron transport and respiration. Defects in this protein cause Friedreich ataxia. Recombinant Frataxin protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: CyaY, FA, FARR, FRDA, X25, FXN, Friedreich ataxia protein. NCBI no.: NP_000135

Molekulargewicht: 21.1 kDa (190aa), confirmed by MALDI-TOF.

Pathways: Transition Metal Ion Homeostasis, Regulation of Cell Size