LAT Protein (AA 28-233) (His tag)

Produktnummer ABIN7279583

Produktdetails

Target: LAT (Linker For Activation of T Cells (LAT))

Protein-Typ: Recombinant

Proteineigenschaft: AA 28-233

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses LAT Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: LAT, 28-233 aa , Human,His tag, E.coli

Reinheit: > 95 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford)

Buffer: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 1mM DTT

Lagerung: 4 °C

Antigendetails

Target: LAT (Linker For Activation of T Cells (LAT))

Andere Bezeichnung: LAT (LAT Produkte)

Synonyme: LAT Protein, lat Protein, LAT1 Protein, pp36 Protein, linker for activation of T-cells Protein, linker for activation of T cells Protein, LAT Protein, lat Protein, Lat Protein

Hintergrund: LAT is an integral membrane protein which is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. LAT is expressed in T lymphocytes in interstitial spaces, platelets and megakaryocytes. LAT is not expressed in B cells, macrophages, plasma cells, monocytes, epithelial histiocytes and dendritic cells. Recombinant human LAT protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: linker for activation of T-cells family member 1 isoform b, LAT1, pp36. NCBI no.: NP_001014987

Molekulargewicht: 24.4 kDa (227aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung