MYL6B Protein (AA 1-208) (His tag)

Produktnummer ABIN667554

Produktdetails

Target: MYL6B (Myosin, Light Chain 6B, Alkali, Smooth Muscle and Non-Muscle (MYL6B))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-208

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses MYL6B Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: MYL6B, 1-208aa, Human, His tag, E.coli

Reinheit: > 95 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay )

Buffer: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 2mM DTT.

Lagerung: 4 °C

Antigendetails

Target: MYL6B (Myosin, Light Chain 6B, Alkali, Smooth Muscle and Non-Muscle (MYL6B))

Andere Bezeichnung: MYL6B (MYL6B Produkte)

Synonyme: MLC1SA Protein, 5730437E04Rik Protein, BC037527 Protein, myosin light chain 6B Protein, myosin, light polypeptide 6B Protein, myosin, light chain 6B, alkali, smooth muscle and non-muscle Protein, MYL6B Protein, Myl6b Protein

Hintergrund: MYL6B is a heavy chain regulator found in smooth muscle and non-muscle Myosin complexes. Contractile activity in smooth muscle is regulated by the calcium/calmodulin-dependent phosphorylation of Myosin light chain by Myosin light chain kinase. MYL6B does not bind calcium during contraction. It is primarily found in a hexamer consisting of four light chains and two heavy chains. It most commonly interacts with Myosin Va, an Actin based motor that can move in large steps. MYL6B is expressed in most tissues with neurons and smooth muscle tissue having the highest expression. Recombinant human MYL6B protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Myosin light chain 6B, MLC1SA. NCBI no.: NP_002466

Molekulargewicht: 25.2 kDa (231aa), confirmed by MALDI-TOF