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RGS17 Protein (AA 1-210) (His tag)

RGS17 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Produktnummer ABIN667548
  • Target Alle RGS17 Proteine anzeigen
    RGS17 (Regulator of G-Protein Signaling 17 (RGS17))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 1-210
    Spezies
    • 4
    • 1
    • 1
    Human
    Quelle
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses RGS17 Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Produktmerkmale
    RGS17, 1-210aa, Human, His tag, E.coli
    Reinheit
    > 90 % by SDS - PAGE
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.0 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 0.1M NaCl,1mM DTT
    Lagerung
    4 °C
  • Target
    RGS17 (Regulator of G-Protein Signaling 17 (RGS17))
    Andere Bezeichnung
    RGS17 (RGS17 Produkte)
    Synonyme
    RGS17 Protein, zgc:92802 Protein, MGC179306 Protein, RGS-17 Protein, RGSZ2 Protein, hRGS17 Protein, 6430507P11Rik Protein, Rgsz2 Protein, regulator of G protein signaling 17 Protein, regulator of G-protein signaling 17 Protein, RGS17 Protein, Rgs17 Protein, rgs17 Protein
    Hintergrund
    RGS17, also known as regulator of G-protein signaling 17, attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. It plays an important role in termination of signalling by mu opioid receptors and development of tolerance to opioid analgesic drugs. Recombinant human RGS17 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Regulator of G-protein signaling 17, hRGS17, RGS-17, RGSZ2. NCBI no.: NP_036551
    Molekulargewicht
    26.5 kDa(230aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
    Pathways
    Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
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