RGS17 Protein (AA 1-210) (His tag)
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- Target Alle RGS17 Proteine anzeigen
- RGS17 (Regulator of G-Protein Signaling 17 (RGS17))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 1-210
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses RGS17 Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Produktmerkmale
- RGS17, 1-210aa, Human, His tag, E.coli
- Reinheit
- > 90 % by SDS - PAGE
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1.0 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 0.1M NaCl,1mM DTT
- Lagerung
- 4 °C
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- Target
- RGS17 (Regulator of G-Protein Signaling 17 (RGS17))
- Andere Bezeichnung
- RGS17 (RGS17 Produkte)
- Synonyme
- RGS17 Protein, zgc:92802 Protein, MGC179306 Protein, RGS-17 Protein, RGSZ2 Protein, hRGS17 Protein, 6430507P11Rik Protein, Rgsz2 Protein, regulator of G protein signaling 17 Protein, regulator of G-protein signaling 17 Protein, RGS17 Protein, Rgs17 Protein, rgs17 Protein
- Hintergrund
- RGS17, also known as regulator of G-protein signaling 17, attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. It plays an important role in termination of signalling by mu opioid receptors and development of tolerance to opioid analgesic drugs. Recombinant human RGS17 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Regulator of G-protein signaling 17, hRGS17, RGS-17, RGSZ2. NCBI no.: NP_036551
- Molekulargewicht
- 26.5 kDa(230aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
- Pathways
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
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