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CLCF1 Protein (AA 28-225) (His tag)

CLCF1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Produktnummer ABIN667531
  • Target Alle CLCF1 Proteine anzeigen
    CLCF1 (Cardiotrophin-Like Cytokine Factor 1 (CLCF1))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 28-225
    Spezies
    • 6
    • 4
    • 3
    Human
    Quelle
    • 9
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses CLCF1 Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Produktmerkmale
    CLCF1, 28-225aa, Human, His tag, E.coli
    Reinheit
    > 90 % by SDS - PAGE
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. 20mM sodium citrate (pH 3.5), 0.4M Urea, 10% glycerol
    Lagerung
    4 °C
  • Target
    CLCF1 (Cardiotrophin-Like Cytokine Factor 1 (CLCF1))
    Andere Bezeichnung
    CLCF1 (CLCF1 Produkte)
    Synonyme
    clc Protein, nr6 Protein, bsf3 Protein, nnt1 Protein, ciss2 Protein, CLCF1 Protein, BSF-3 Protein, BSF3 Protein, CISS2 Protein, CLC Protein, NNT-1 Protein, NNT1 Protein, NR6 Protein, Bsf3 Protein, Clc Protein, cardiotrophin like cytokine factor 1 Protein, cardiotrophin-like cytokine factor 1 Protein, clcf1 Protein, CLCF1 Protein, Clcf1 Protein
    Hintergrund
    CLCF1, also known as cardiotrophin-like cytokine factor 1, belongs to the interleukin 6 family of cytokines, which are involved in cell signaling through phosphorylation of gp130. CLCF1 has a sequence of 225-amino acids with a 27-aa signal peptide, a molecular mass of 22 kDa in mature form, and the highest homology to cardiotrophin-1 and ciliary neurotrophic factor. CLCF1 can be actively secreted from cells by forming a complex with soluble type I CRLF1 or soluble CNTFR. Defects in CLCF1 cause cold-induced sweating syndrome 2 (CISS2). This syndrome is characterized by a profuse sweating after exposure to cold as well as congenital physical abnormalities of the head and spine. Synonyms: Cardiotrophin-like cytokine factor 1, BSF-3, BSF3, CISS2, CLC, NNT-1, NNT1, NR6. NCBI no.: NP_037378
    Molekulargewicht
    24.6 kDa (219aa)
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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